Nonoccupational Postexposure Prophylaxis (NPEP)
NPEP, or PEP, is an antiviral treatment regimen that can prevent HIV infection after exposure to the HIV virus. Health care workers have been using PEP since 1986 whenever they have been exposed to a large amount of blood, gotten blood in an open wound, or been stuck with a contaminated needle.
Occupational PEP (used for exposure on the job) prevents HIV infection in about 80% of people who seek medical care immediately after exposure. Full patient compliance is necessary for successful treatment, which lasts for several months and requires three daily doses. It costs $600 - $1000 and can cause serious side effects including nausea, fatigue, headache, and general malaise. There is no scientific evidence that shows its effectiveness after sexual exposure.
Information and advice can be obtained by calling the toll-free 24-hour PEPLine at 1-888-HIV-4911 (1-888-448-4911), or by calling Fenway Community Health at 617-927-6100.
General STD Information and Prevention Suggestions
- It is safe and smart to ask a partner about STD history, HIV, and STD prevention before having sex.
- HIV reinfection is possible. People infected with one strain of the virus can contract and spread different strains during unprotected sex. Compounded infection affects treatment.
- Many new HIV infections are resistant to medication.
- Hepatitis A and B vaccinations are highly recommended for men who have sex with men. Vaccination can be obtained from a primary care provider.
- HIV-negative people can maintain their status by avoiding contact with semen and blood.
- It may be helpful to keep condoms around if the chance exists for spontaneous or unplanned sex.
- Use a water-based lubricant (e.g., KY Jelly) that does NOT contain nonoxonyl-9 (N9).
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